Windows only, sorry. It seems that very few people even know about the Windows-E combination to start an Explorer instance. Well, this open-source freeware lets you assign any program to any Windows-key combination press.
qliner is a free, open-source program which lets you graphically bind any Windows+key combination press to launch or focus any program. They have some really cool features, which are not even found on the paid programs, such as a graphic on-screen keyboard that you can just drag programs onto to create the bindings.
Also, in the interest of ergonomics, it will re-map the Caps-Lock key to the Windows key, thus allowing you to turn the relatively useless Caps-Lock into a pinky-friendly, easy-to-press combination key sequence.
This program is quite smooth and polished and serves to replace other programs such as WinKey, which are not quite as graphically interesting and have fewer features.
Read about and download qliner – you’ll probably like it if you enjoy keyboard shortcuts, and what power-user doesn’t? 😉